Artrose patiënten voelen dagelijks veel pijn
Met 1,1 miljoen patiënten is artrose de meest voorkomende reumatische aandoening in Nederland. Artrose is een kraakbeen- en gewrichtsaandoening waarbij men bij beweging last kan hebben van een bepaald gewricht. In het geval van artrose kan dit gewricht stijf of stram aanvoelen. De aandoening ontstaat doordat er minder kraakbeen wordt aangemaakt dan dat er verloren gaat, hierdoor ontstaat er slijtage en ontstekingen. Gewrichten als handen, knieën en schouders kunnen dan pijnlijk aanvoelen.
Uit een onderzoek, uitgevoerd door het Reumafonds i.s.m. Erasmus MC Huisartsengeneeskunde, is gebleken dat 84% van de deelnemende artrosepatiënten, dagelijks pijn ervaart. Van de patiënten die meededen aan het onderzoek, heeft 73% artrose in de hand, 57% in de wervelkolom bij de rug of de nek en 56% heeft artrose in de knie. Het onderzoeksteam onderzocht welke dosering en frequentie van verschillende pijnbestrijdingsmiddelen het beste werken bij artrose.
Naast het feit dat 84% van de deelnemers dagelijks pijn ervaart is verder uit het onderzoek gebleken dat de pijnbestrijding die de patiënten gebruiken in de meeste gevallen niet genoeg werkt. Slechts 30% geeft aan dat de medicatie wel goed werkt. Zo blijken de meeste patiënten nog steeds pijnstillers te slikken tegen deze aandoening; patiënten gebruiken paracetamol, slikken of smeren een NSAID pijnstiller of gebruiken een opiaat. Maar lang niet voor iedereen dus zijn deze pijnstillers genoeg om dagelijks pijnvrij te zijn. [1]
Is er een oplossing voor de pijn?
In de meeste gewrichten zijn de uiteinden van die botten bekleed met kraakbeen. Kraakbeen zorgt in de gewrichten voor bescherming van de botten (schokabsorptie) en helpt bij de glijbeweging.
In vivo onderzoek uitgevoerd aan de universiteit van Rochester Medical Center (USA), bevestigt de unieke voordelen van specifieke aminozuren in ondersteuning van gezonde gewrichten door regeneratie van kraakbeen en zijn belangrijke anti-inflammatoire (ontstekingsremmende) werking [2], terwijl uit andere studies is gebleken dat deze aminozuren de aanmaak van nieuw kraakbeen bevorderen [3].
Productie van bindweefsels waaronder kraakbeenweefsel is het hoogste in de leeftijd tot 25 jaar. Daarna kan een geleidelijke achteruitgang van de collageenvezels in weefsels ontstaan, waardoor kraakbeen bijvoorbeeld versneld slijt door ongeval, overbelasting, slijtage en/of ouderdom.
Een aantal recente studies toont aan dat de behandeling van artrose en reumatoïde artritis met aminozuren zeer effectief blijkt te zijn, die het bindweefsel ondersteunen en gezonde gewrichten bevorderen [4], terwijl weer in andere studies is bevestigd dat de combinatie van specifieke aminozuren, degeneratie van het gewricht helpt te voorkomen en pijn helpt te verminderen [5].
Eiwitten worden in al ons bindweefsel gevonden. Eiwitten bestaan uit aminozuren. In de natuur zijn ongeveer 500 verschillende aminozuren geïdentificeerd, waarvan een beperkt aantal in menselijke eiwitten voorkomt.
Lees meer over deze aminozuren…
[1] Voetnoot Studies
Bron onderzoek: http://actueel.reumafonds.nl/ruim-900000-artrosepatienten-hebben-dagelijks-pijn/
[2] Voetnoot Studies
Dar Q.A. et al. 2014, Oral hydrolysed type I collagen induces chondroregeneration and inhabits synovial inflammation in murine posttraumatic osteoarthritis, Osteoarthritis and Cartilage. 24:5532-5533.
[3] Voetnoot Studies
Jiang, et al. 2014. Treatment of Knee Osteoarthritis: A Double-Blind Randomized, Placebo-Controlled Study. Agro Food Industry Hi Tech 25(2): 20–21.
T.E. McAlindon 2011, Change in knee osteoarthritis cartilage detected by delayed gadolinium enhanced magnetic resonance imaging following treatment with collagen hydrolisate: a pilot randomized controlled trial.
[4] Voetnoot Studies
Moskowitz, R., 2000. Role of collagen peptides in bone and joint disease. Seminars in Arthritis and Rheumatism, 30: 87-99.
Benito-Ruiz P. et al., 2009. A randomized controlled trial on the efficacy and safety of a food ingredient, collagen hydrolysate, for improving joint comfort. International Journal of Food Sciences and Nutrition, 60:99-113.
Henrotin Y. et al., 2011. Nutraceuticals: do they represent a new era in the management of osteoarthritis? – a narrative review from the lessons taken five products. Osteoarthritis and Cartilage, 19: 1-21.
Ragle R.L. et al., 2012. Nutraceuticals in the management of osteoarthritis: a critical review. Drugs & Aging, 29: 717-731.
Clark, K.L. et al., 2008. 24-Week study on the use of collagen hydrolysate as a dietary supplement in athletes with activityrelated joint pain. Current Medical Research and Opinion, 24: 1485-1496.
[5] Voetnoot Studies
Van Vijven, J.P.J. et al., 2012, Symptomatic and chondroprotective treatment with collagen derivatives in osteoarthritis: a systematic review, Osteoarthritis and Cartridge, 20(8): 809-821.
Ragle, R.L., and Sawitzke, A.D., 2012, Nutraceuticals in the management of osteoarthritis: a critical review, Drugs Aging, 29(9): 717–731.
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