Wetenschap: Calcium belangrijk bij osteoporose… Aminozuren ook!

Posted on by Maarten van Wersch
12 mei

Osteoporose (botontkalking) is een aandoening waarbij de botdichtheid is verlaagd als gevolg van afgenomen botmassa. De aandoening komt veel voor bij postmenopauzale vrouwen: osteoporose treft ongeveer één op de drie vrouwen ouder dan 50 jaar en één op de vijf mannen ouder dan 50 jaar.

Waarom calcium

Zodra het lichaam een tekort heeft aan calcium, neemt het calcium weg uit de beenderen. Door ervoor te zorgen dat via voeding en supplementen genoeg calcium wordt opgenomen, is er steeds voldoende calcium aanwezig in het lichaam.

Op de leeftijd van 30 jaar zijn de botten het sterkst en bereiken ze hun hoogste dichtheid. Tot dan is het zeker ook belangrijk voor kinderen en volwassenen om voldoende calcium op te nemen.

Opname van voldoende calcium blijft ook belangrijk na je dertigste… In geval van ongezonde eetgewoontes of gebrek aan nodige voedingstoffen in het dieet, kan het lichaam de botten als energiereserve gaan gebruiken. Het is natuurlijk niet zo erg als dit een keer gebeurt. Zorg in dat geval voor extra calciuminname om het verlies uit je botten te compenseren. Maar wordt gedurende langere periodes ongezonde voeding gegeten, dan blijft het lichaam de botten belasten en ligt mogelijk botontkalking op de loer.

Voor vrouwen die de menopauze bereiken is calciuminname essentieel om botontkalking tegen te gaan. Dan worden er namelijk minder vrouwelijke hormonen aangemaakt en het waren juist die hormonen die er voor zorgden dat de afbraak van botweefsel afgeremd werd. Na de overgang breekt het lichaam de botten dus sneller af, waardoor ze brozer worden.

Voldoende eiwitten op het menu, staat dus garant voor het krijgen en onderhouden van stevige botten. Vooral door de consumptie van vlees, vis, eieren, bonen, linzen en walnoten. Daarbij kun je ook kiezen voor een voedingssupplement. Inmiddels breed gedragen is de effectieve werking van aminozuren (eiwitten); inname hiervan draagt bij tot botaanmaak. In talrijke studies [1] is bevestigd dat door dagelijkse inname van uitgekiende aminozuren de botcellen die belast zijn met botvorming (osteoblasten) voorkeursmatig worden gestimuleerd, vergeleken met cellen die betrokken zijn bij botafbraak (osteoclasten), hetgeen leidt tot een toename van botvorming.

Bones Vitalis Botten & Kraakbeen

Probeer nu

Advertentie

Wat doen aminozuren

Het zijn aminozuren die er voor zorgen dat ons lichaam wordt voorzien van bouwstenen die helpen bij de normale vorming van bindweefsels. Structuren die vallen onder bindweefsel zijn onder meer botten, pezen, spieren, gewrichtsbanden, gewrichtskapsel, gewrichtskraakbeen en botten.

In voeding zitten eiwitten. Eiwitten bestaan uit aminozuren. Bij de spijsvertering worden de aminozuren onder invloed van enzymen, uit voeding vrijgemaakt. De aminozuren worden via de darmhaarvaten en de poortader naar de lever gevoerd. Een deel van de aminozuren zal de lever onveranderd verlaten, een deel zal in de lever worden omgezet in andere aminozuren (transaminering).

Uit de vrijgekomen aminozuren kan het organisme zijn eigen specifieke eiwitten (collageen, etc.) opbouwen. Het aanmaken (de synthese) van eiwitten binnen een organisme wordt eiwitsynthese genoemd. Hierbij zijn het de osteoblasten die de organische bestanddelen van de botmatrix maken. Osteoblasten produceren collageen, proteoglycanen en glycoproteÏnen.

Botmetabolisme (proces van botaanmaak en botafbraak) vervangt jaarlijks circa 15% van de botmassa bij gezonde volwassenen. In een recente studie [2] is bevestigd dat onevenwichtige verhoudingen van botafbraak en botopbouw leiden tot meer botverlies dan botformatie. De studie herbevestigt dat inname van uitgekiende aminozuren, botvormende cellen (osteoblasten) activeert en botafbraak vermindert.

Aminozuren (eiwitten) zijn ook verkrijgbaar als voedingssupplement. Voedingssupplementen worden als levensmiddel geclassificeerd. Ze hebben dan ook – afgezien van eventuele voedselallergie of voedselintolerantie – geen bijwerkingen. Lees meer over deze supplementen…

Aminozuren en meer…

[1] Voetnoot Studies

Mizuno, M. et al., 2001. Osteoblast-related gene expression of bone marrow cells during the osteoblastic differentiation induced by type I collagen. Journal of Biochemistry, 129: 133-138.

Lynch, M.P. et al., 1995. The influence of type I collagen on the development and maintenance of the osteoblast phenotype in primary and passaged rat calvarial osteoblasts: modification of expression of genes supporting cell growth, adhesion, and extracellular matrix mineralization. Experimental Cell Research, 216: 35-45.

Daneault, A. et al, 2014, Hydrolyzed collagen contributes to osteoblast differentiation in vitro and subsequent bone health in vivo. Osteoarthritis and  Cartilage 22: S131.

Andrianarivo, A.G. et al., 1992. Growth on type I collagen promotes expression of the osteoblastic phenotype in human osteosarcoma MG-63 cells. Journal of Cellular Physiology, 153: 256-265.

[2] Voetnoot Studies

Daneault, A. et al., 2015. Biological effect of hydrolyzed collagen on bone metabolism. Critical Reviews in Food Science and Nutrition, 10: 1040- 8398

70 thoughts on “Wetenschap: Calcium belangrijk bij osteoporose… Aminozuren ook!”

  1. minecraft zegt:

    I don’t even know how I finished up here, but I assumed this publish
    was once good. I don’t recognise who you’re however certainly
    you’re going to a well-known blogger in the event you
    aren’t already. Cheers!

  2. minecraft zegt:

    Thank you for the auspicious writeup. It in fact was a amusement account it.
    Look advanced to more added agreeable from you! By the way, how could we communicate?

  4. minecraft zegt:

    You’re so cool! I don’t suppose I’ve truly read through something like that before.

    So wonderful to discover another person with some genuine thoughts on this subject.
    Really.. thanks for starting this up. This website is something that’s needed on the internet, someone with a little originality!

  5. minecraft zegt:

    Hi there! I just wanted to ask if you ever have any issues with hackers?
    My last blog (wordpress) was hacked and I ended up losing a few months of
    hard work due to no back up. Do you have any solutions to protect against hackers?

  6. minecraft zegt:

    I seriously love your site.. Excellent colors & theme.
    Did you make this website yourself? Please reply back as I’m wanting to create my own website and
    would love to know where you got this from or what the theme
    is called. Many thanks!

  9. minecraft free download 2018 zegt:

    Simply wish to say your article is as astonishing.
    The clarity in your post is simply nice and i can assume you are an expert on this subject.

    Well with your permission allow me to grab your RSS feed to
    keep up to date with forthcoming post. Thanks a million and please carry
    on the gratifying work.

  10. minecraft free download 2018 zegt:

    Hey there! Someone in my Facebook group shared this website with us so I came to give it a look.
    I’m definitely enjoying the information. I’m book-marking and will be tweeting this to my followers!
    Superb blog and amazing style and design.

  12. minecraft free download 2018 zegt:

    you’re truly a just right webmaster. The site loading speed is amazing.
    It kind of feels that you are doing any unique trick. In addition,
    The contents are masterpiece. you’ve performed
    a magnificent task in this topic!

  13. minecraft free download 2018 zegt:

    I am not sure where you are getting your information, but good topic.
    I needs to spend some time learning much more or
    understanding more. Thanks for excellent information I was looking for this info for my mission.

  14. minecraft free download 2018 zegt:

    Admiring the commitment you put into your website
    and in depth information you provide. It’s great to come across a blog every once in a while that isn’t
    the same outdated rehashed information. Wonderful read!

    I’ve bookmarked your site and I’m adding your RSS feeds to my Google account.

  16. tinder dating site zegt:

    Hey! I know this is kinda off topic but I was wondering which blog platform are you using for this website?
    I’m getting fed up of WordPress because I’ve had problems with hackers and I’m looking at options for another
    platform. I would be great if you could point me
    in the direction of a good platform.

  17. tinder dating site zegt:

    I am curious to find out what blog system you have been working with?
    I’m having some small security problems with my latest blog and I would like to find something more secure.
    Do you have any suggestions?

  19. minecraft secret free download zegt:

    It’s perfect time to make some plans for the longer
    term and it is time to be happy. I have learn this publish and if I may just I wish to recommend
    you some fascinating things or tips. Maybe you could write subsequent articles referring to this article.

    I desire to learn more things about it!

  22. Health Benefits of Coconut Oil zegt:

    Pretty section of content. I just stumbled upon your website and in accession capital to assert
    that I acquire actually enjoyed account your blog posts. Anyway I’ll be subscribing to your feeds and even I achievement you
    access consistently fast.

  25. Benefits of Coconut Oil zegt:

    hello!,I like your writing very a lot! proportion we keep in touch extra about your article on AOL?
    I require a specialist on this house to resolve my problem.
    Maybe that’s you! Having a look forward to peer you.

  26. Health Benefits of Coconut Oil zegt:

    Hey! This is my first visit to your blog! We are a collection of volunteers
    and starting a new project in a community in the same niche.
    Your blog provided us useful information to work on.
    You have done a marvellous job!

  27. Benefits of Coconut Oil zegt:

    The other day, while I was at work, my sister stole my iPad and tested to see if
    it can survive a 30 foot drop, just so she can be a youtube sensation.
    My apple ipad is now destroyed and she has 83 views. I know this is completely off
    topic but I had to share it with someone!

  29. Coconut Oil Benefits zegt:

    Hello There. I found your blog using msn. This is a very well
    written article. I’ll be sure to bookmark it and come
    back to read more of your useful information. Thanks for the post.
    I’ll definitely comeback.

  30. descargar facebook zegt:

    Greetings! I’ve been reading your web site for a long time
    now and finally got the bravery to go ahead and give you a shout out
    from Porter Tx! Just wanted to mention keep up the good job!

  31. quest bars cheap zegt:

    Hello, Neat post. There’s a problem along with your web site in web explorer, could test this?
    IE still is the market chief and a big component of
    other folks will leave out your wonderful writing because of this problem.

  32. quest bars cheap zegt:

    Pretty element of content. I simply stumbled upon your
    web site and in accession capital to say that I get actually loved account your blog posts.

    Any way I’ll be subscribing in your augment and even I
    success you access consistently fast.

  34. quest bars cheap zegt:

    Quest bars cheap fitnesstipsnew1 quest bars cheap 516999410492780544 quest
    bars cheap
    It’s amazing for me to have a web page, which is useful for my
    know-how. thanks admin quest bars cheap fitnesstipsnew1 quest bars cheap 516999410492780544 quest bars cheap

  35. Quest Protein Bars zegt:

    I like the valuable information you supply on your articles.
    I’ll bookmark your blog and check once more here frequently.
    I’m relatively sure I will be informed plenty of new stuff proper here!
    Best of luck for the following!

  36. quest bars zegt:

    Hi would you mind stating which blog platform you’re using?

    I’m planning to start my own blog in the near future but
    I’m having a tough time choosing between BlogEngine/Wordpress/B2evolution and Drupal.
    The reason I ask is because your design seems different then most blogs and I’m looking for
    something completely unique. P.S My apologies for
    getting off-topic but I had to ask!

  39. What Equipment is Needed for Sling TV zegt:

    I know this if off topic but I’m looking into starting my own blog and was wondering what all is needed to get
    setup? I’m assuming having a blog like yours would cost a pretty penny?

    I’m not very web smart so I’m not 100% positive. Any recommendations or advice would be greatly appreciated.
    Cheers

  40. Sling TV zegt:

    I got this site from my friend who shared with me on the topic of
    this web page and at the moment this time I am browsing this site
    and reading very informative content at this time.

  44. Sling TV zegt:

    Hey! This post couldn’t be written any better! Reading through this
    post reminds me of my old room mate! He always kept talking about this.

    I will forward this write-up to him. Pretty sure he will
    have a good read. Thank you for sharing!

  49. What Equipment is Needed for Sling TV zegt:

    An impressive share! I’ve just forwarded this onto a co-worker who had been doing
    a little homework on this. And he in fact bought me breakfast because I
    found it for him… lol. So let me reword this…. Thank YOU for the meal!!
    But yeah, thanx for spending the time to discuss this matter here on your internet site.

  51. descargar facebook zegt:

    Do you have a spam problem on this blog; I also am a blogger, and I was curious about your situation; many of us have developed some nice procedures and we are looking to trade solutions with other folks,
    please shoot me an e-mail if interested.

Reacties zijn gesloten.